Centriole

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What is the Function of the Centriole?

Centriole plays a crucial role at the time of cell division. At the time of cell division, centrioles replicate to form two centrosomes, each with two centrioles. The two centrosomes then move in the opposite direction towards the opposite ends of the nucleus. From each centrosome, some thread like microtubules appear, which are known as spindle or mitotic spindle. During cell division, the single parent cell divides itself into two daughter cells, and the spindle is responsible for separating or pulling the replicated chromosomes to the two daughter cells. So, centrioles helps in the organization of the mitotic spindle, as well as the completion of cytokinesis.

Centrioles as a part of centrosome also play a significant role in cellular organization, especially in organizing the microtubules in the cytoplasm and the spatial arrangement of the cell. Even the position of the nucleus is determined by the position of the centrioles. The mother centriole (the original or older centriole, from which a new centriole develops during cell division) determines the position of cilia and flagella in the organisms with these organelles. In fact, the mother centriole become the basal body in these organisms. A failure of the cell to make functional cilia and flagella with the help of centrioles has been found to be associated with several developmental and genetic diseases. Another important fact about centriole functions is that during mammalian development, proper orientation of cilia via centriole positioning toward the posterior of embryonic node cells is considered as quite crucial for the establishment of left-right asymmetry. Know more about the
•Cell Division Stages
•Cell Nucleus: Structure and Functions
•Structure and Functions of the Cytoplasm